Weight loss led to reduction in inflammation

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Weight loss reduction surgeries showing long-term health benefits for adults and teens, studies say

“Both obesity and inflammation have been shown to be related to several types of cancer, and this study shows that if you reduce weight, you can reduce inflammation as well,” said Anne McTiernan, M.D., Ph.D., director of the Prevention Center at the Fred Hutchinson Cancer Research Center in Seattle, Wash. Women in the trial who were assigned to a weight loss intervention had a goal of 10 percent weight reduction during the course of one year achieved through a diet intervention with or without aerobic exercise . “So this program was highly achievable and reproducible. We are not talking about drastic weight loss,” said McTiernan. The researchers measured levels of C-reactive protein, serum amyloid A, interleukin-6, leukocyte and neutrophil in 439 women. At the end of one year, C-reactive protein reduced by 36.1 percent in the diet-alone group and by 41.7 percent in the diet and exercise group.
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“It shows what we have seen — that bariatric surgery is the only way to take the weight off and keep it off,” said Nusbaum, whose center performs 600 to 800 procedures a year. The study focusing on children is especially important to stress how safe the procedures are, particularly the gastric banding which can be reversed, Nusbaum said. “One of my concerns has always been whether a 15 or 16 year old can make a decision about a permanent surgery when they may not be mature enough,” he said. The national Institute studies on weight loss reduction surgeries, launched in 2003 with adults and 2007 among teens, are among the longest and broadest of their kind, according to the journal articles.
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